ECL: An Exhaustive Search Tool for the Identification of Cross-Linked Peptides Using Whole Database (Deprecated)
About ECL |
ECL is short for Exhaustive Cross-Linked peptides identification. Has been deprecated. Please use ECL2. |
Where to download ECL and how to use it? |
Executable file can be downloaded from: https://github.com/fcyu/ECL/releases. Source code: https://github.com/fcyu/ECL Requirement: Java version >= 1.7. Usage: java -Xmx25g -jar ECL.jar parameter.def data_file.mzXML parameter.def: Parameter file. Can be download along with ECL. data_file.mzXML: Spectra data file (mzXML). For any enquiry, please contact Fengchao Yu at fyuab@connect.ust.hk |
Example spectra and database |
Cross-linking of two synthetic peptides: ECL_try.zip Usage instruction:
java -Xmx32g -jar D:\ECL_try\ECL.jar D:\ECL_try\parameter.def D:\ECL_try\XL_midK.mzXML
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About ECLViewer (a replacement of ECLAnnotator) |
ECLViewer is a software viewing ECL results. |
Where to download ECLAnnotator and how to use it? |
Executable file: https://bioinformatics.hkust.edu.hk/ecl/ECLViewer.zip Requirement: Microsoft .NET Framework 4.5.2 link. Usage: Unzip "ECLVIewer.zip", and double-click "ECLViewer.exe". The spectra file should be MGF format (converted by TPP or ProteoWizard) For any enquiry, please contact Fengchao Yu at fyuab@connect.ust.hk |
Related Publication |
Fengchao Yu, Ning Li*, Weichuan Yu*. *Joint corresponding authors.
"ECL: An Exhaustive Search Tool for the Identification of Cross-Linked Peptides Using Whole Database". BMC Bioinformatics, 17:1-8, 2016, [link] |