SeaPIC: Searching for Post-translational Modification in the Crosslinked peptide-spectrum matches.
| About SeaPIC |
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The detection of post-translational modifications (PTMs) in cross-linking mass spectrometry holds significant importance as it provides valuable insights into the impact of PTMs on protein-protein interactions and the alteration of protein structural conformations. We designed the SeaPIC for PTM investigation in cross-linking datasets. SeaPIC has proven its effectiveness by uncovering previously overlooked PTM information in publicly available datasets.
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| Related Publication |
| C. Zhou, S. Lai, S. Dai, P. Zhao, N. Li and W. Yu.
"Identification of Post-translational Modifications in Cross-linking Mass Spectrometry Data", ?????, doi: https://doi.org/xxxxxxxxxxx. |
| Where to download SeaPIC |
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The source code and test data are available at:
Source code & test data
(updated Oct. 14, 2024)
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| How to use it? |
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Find the details in README.md from the source file. For any enquiry, please contact ZHOU, Chen (czhouau@connect.ust.hk). |