Identification of Post-translational Modifications in Cross-linking Mass Spectrometry Data

About PTMSeeker

The detection of post-translational modifications (PTMs) in cross-linking mass spectrometry holds significant importance as it provides valuable insights into the impact of PTMs on protein-protein interactions and the alteration of protein structural conformations. We designed the PTMSeeker for PTM investigation in cross-linking datasets. PTMSeeker has proven its effectiveness by uncovering previously overlooked PTM information in publicly available datasets.


Related Publication
C. Zhou, S. Lai, S. Dai, P. Zhao, N. Li and W. Yu.
"Identification of Post-translational Modifications in Cross-linking Mass Spectrometry Data",
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Where to download PTMSeeker

The source code and test data are available at: (updated Jan. 12, 2024)
Source code & test data:       PTMSeeker_and_testdata.zip


How to use it?

Find the details in README.md from the source file.
For any enquiry, please contact ZHOU, Chen ( czhouau@connect.ust.hk).